Bimatoprost Eye Drops
Glaucoma is a serious ophthalmic pathology or a medical condition induced by higher-than-normal pressure inside the eye – a condition called ocular hypertension. Glaucoma refers to a group of related eye disorders that all cause damage to the optic nerve that carries information from the eye to the brain. Despite the fact that this disease carries a lot of implications for eyesight health, a clinical course is asymptomatic. If untreated or uncontrolled, glaucoma first causes peripheral vision loss and eventually can lead to blindness. And because most cases of glaucoma have few or no early symptoms, about half of Americans with glaucoma don’t know they have it.
Glaucoma is the second-leading cause of blindness in the U.S. (behind macular degeneration), and the second-leading cause of blindness worldwide (behind cataracts).
Symptoms of glaucoma include simple discomforts such as eye pain, burning, tired feeling in the eyes. Patients with complain of similar symptoms are usually checked for ocular hypertension, which when high, needs proper glaucoma treatment. Surgery is one option, but for obvious reasons it is not the most preferred one. A breakthrough in this field of optics was the release of Bimatoprost. Use of Bimatoprost with proper prescription and precautions can reduce the intraocular pressure and stop glaucoma.
Bimatoprost is a drug used for uninvasive the treatment of glaucoma. This drug is sometimes referred to be cosmetical as it is often used for another purpose: increasing the length of the lashes. Bimatoprost is an unsaturated fatty acid, similar to hormones. It helps to maintain the balance of inflow and outflow of ocular fluid in the eye. The imbalance of ocular fluid increases pressure, and thus leads to poor blood supply to the eye. This is turn affects the working of the optical nerve. The drug has a direct effect on the channels through which the hydatoid leaves the eyeball. It expands these channels, accelerates the reduction of intraocular pressure and thus reduces the pressure to the eyes.
Bimatoprost acts as a hormone and thus has some cosmetic effect at times. Clinical studies show that it can lead to significant increase in the number an length of eyelashes within a few weeks. Scientists discovered that Bimatoprost affects the follicles in the eyelids and increase their number. Nowadays Bimatoprost is also used as a natural solution to make eyelashes grow faster. Though it is recommended to consult a doctor and get a professional test before doing so.
Working of the Medication
Bimat 0.03% contains the active ingredient Bimatoprost 0.03% and it is considered a prostaglandin analogs type of treatment. Bimat 0.03% (Generic Bimatoprost 0.03%) works by lowering the pressure in the eye by increasing the flow of natural eye fluids out of the eye. By Regulating eye pressure Bimat 0.03% (Generic Bimatoprost 0.03%) treats certain types of glaucoma and help prevent blindness.
Bimatoprost belongs to a class of medications called prostamides. It is available in eye-drop form and is used to reduce the pressure inside the eye for people with open-angle glaucoma or intraocular hypertension (increased pressure in the eye).
During the normal functioning of the eye, Fluid is constantly being formed and drained. Improper draining of this fluid causes increased pressure inside the eye. Bimatoprost works by increasing the flow of fluid out of the eye. It starts to work within 4 hours of use.
Brand Name: Bimat Eye Drops
Generic Name: Bimatoprost 0.03% (latisse)
Bimatoprost is available in different concentrations, most common ones being 0.01% and 0.03% . The first approved generic Bimatoprost was launched under the brand name of Bimatoprost ophthalmic, approved by the FDA in the following formulation(s):
Bimatoprost-solution/ eye drops;ophthalmic
Strength(s): 0.01% [RLD] and 0.03% [latisse]
Therapeutically equivalent version of Bimatoprost is available in most other countries. In its generic form, the medication may be available under multiple brand names and/or in several different forms. The available forms might differ as per the brand manufacturing it. Usually the contents do not differ, but some versions might not prove equally useful for all symptoms of glaucoma.
Indications for the Use:
• Open-angle glaucoma
• Angle-closure glaucoma
• Control of ocular hypertension
Unlike most eye drops Bimatoprost eye drops can treat all forms of glaucoma. The drug has a general effect and acts equally well in pathologies of the visual organs caused by ocular hypertension.
0.03% Ophthalmic Solution
0.03% here represents the strength of the solution, i.e., each ml of clear, colourless, sterile solution contains bimatoprost 0.3 mg.
Non medicinal ingredients: benzalkonium chloride, citric acid monohydrate, purified water, sodium chloride, and sodium phosphate dibasic heptahydrate. Sodium hydroxide or hydrochloric acid may be added to adjust ph.
0.01% Ophthalmic Solution
Each ml of clear, colourless, sterile solution contains bimatoprost 0.1 mg.
Non medicinal ingredients: benzalkonium chloride 0.2 mg as preservative, sodium chloride, sodium phosphate dibasic heptahydrate, citric acid monohydrate, and purified water. Sodium hydroxide and/or hydrochloric acid may be added to adjust ph.
Treatment of glaucoma is a long and difficult process and the therapy might last for a few months at a stretch. Bimatoprost is used as an eye drop and must be instilled 1-2 times a day, 1 drop per use. If the daily dose is twice, it must be scheduled at a 12 hour gap. If higher concentration drug is used, it must not be taken more than once a day. The dose might also differ from individual to individual, depending on the severity of the case and physical attributes. A doctor must be consulted on how and when the medication must be used.
To use the eye drops:
• Before using the medicine, make sure are hands are washed. To avoid contamination, do not let the dropper tip touch the eye, hand or any other surface.
• Bimatoprost contains contents that might damage contact lenses. It is advisable to remove them before using the eye drops. 15 minutes gap should be observed after each dose before putting lenses back.
• Tilt the head back and upwards. Gently pull the lower eyelid down and away from the eye to form a pouch. Apply one drop of the medicine into the pouch
• Gently apply pressure to the inner corner of the eye (at the bridge of the nose) for about 30 seconds (this is called nasolacrimal occlusion). This prevents the medication from dripping down through the tear duct and entering the bloodstream, which could cause some side effects.
• Repeat with the other eye, if prescribed by the physician.
• 5 minutes gap must be observed if any other eye drop needs to be used.
In case a dose is missed, it must be instilled as soon as possible and regular schedule must be continued. If the time gap is longer, simply take the next dose. Do not instil a double dose to make up for a missed one.
The dosage must be regular and timed in order to get the most benefit from it. It is important to continue using Bimatoprost even if symptoms of glaucoma are over as most people with glaucoma or high pressure in the eye do not have symptoms.
Storage and Disposal
Bimatoprost, both original and generic versions, must be stored at room temperature and kept out of the reach of children. It must not be used after 28 days of opening the bottle.
Disposal of the medicine should not be careless. Attention must be paid not to drain it down wastewater or with household garbage.
Warnings and Precautions:
• Contact lenses must be removed before using Bimatoprost eye drops.
• Pregnant and breastfeeding mothers must consult the doctor before using Bimatoprost, even though it has not been shown to affect the foetus in anyway .
• Allergy to contents of generic Bimatoprost is rare, but in case of such a situation, the medication must be stopped immediately and referred to a doctor
• Eye changes: Bimatoprost may, in some cases, gradually change the colour of the eye, increasing the amount of brown pigment in the iris (coloured part of the eye). The colour change is permanent though cases of injury are currently unknown.
• Kidney and liver function: people with kidney or liver disorders or reduced kidney function should consult the doctor before taking Bimatoprost. Though serious effects have not been noted, it is recommended to stay under medical supervision.
• Children: The safety and effectiveness of using this medication have not been established for children.
Allergy to certain components or body suitability define side effects as per the patients . The following side effects have been reported by at least 1% of people taking this medication. Most of these are trivial and not long lasting. In case of severe and bothersome effects, medical help is needed.
• A feeling of something in the eye
• Burning eyes
• Dry eyes
• Excessive hair growth
• Eye irritation such as itching, redness, or stinging
• Longer eyelashes
• Redness of the eyelid
Some side effects that need immediate attention of the pharmacist are also listed below. Most of these cases are rare, but prevention is better than cure
• Darkening of eyelid skin colour
• Eye pain
• Increased blood pressure
• Increase in brown colour in coloured part of eye (the iris)
• Inflammation of the eyelid
• Sensitivity of eye to light
• Vision problems (e.g., decrease acuity, blurred vision)
In case of symptoms other than the ones listed above, it is advisable to consult the doctor for suitable guidelines.
Interaction with Other Drugs
Bimatoprost might, in some cases, react with certain other medications. An interaction between two medications does not always mean that it can cause serious problems. It is just safe to take necessary precautions. Some of these are :
• Nonsteroidal anti-inflammatory medications (e.g., diclofenac, ibuprofen, ketorolac, naproxen)
PS: Medications other than those listed above may also interact with this medication
If a patient is consuming any of the above components, it is recommended to consult the doctor. A professional can consider specific situations and give recommendations based on that.
Possible Adverse Effects
Bimatoprost ophthalmic solution can permanently change the eye colour, changing the colour of iris to brown. It can also cause darkening of the eyelid skin and thickening of eyelashes. In some cases, the effects maybe reversible after the treatment is stopped. The long-term effects of increased dark colouring are not known.
Bimatoprost belongs to the class of medicines called Prostaglandin analogs. Almost all prostaglandin analogs, including bimatoprost, have been reported to cause inflammation inside the eye. Existing inflammation might become worse by use of Bimatoprost.
Treatment with Bimatoprost ophthalmic solution might, in rare cases, cause a condition called Macular edema which is swelling of the macula, including cystoid macular edema. All forms of Bimatoprost including generic Bimatoprost, should be used with caution in patients without a natural lens, in patients with a torn posterior lens capsule who have an artificial lens implant, or in patients with known risk factors for macular edema. Patients who have had eye surgery, eye trauma or infection should not use bimatoprost without consultation of a physician.
Treatment of glaucoma is long and may extend up to months. For a full course of treatment, several bottles of Bimatoprost eye drops will be needed. Buying from the local drug pharmacy might cost a small fortune . Buying Bimatoprost opthalmic solution online can help saving a lot of money. Several online stores even offer discount coupons while some offer a lower price. Almost 50% costs can be cut down if proper online channels are used. A 2.5 ml of Bimatoprost or generic Bimatoprost can cost somewhere between 10$ to 45$, depending on the firm chosen by the user. Several sites like drugs.com offer discount coupons which are accepted by most US pharmacies. The terms of this website are specific and clear. In the united states of America, the price guide is based on using the Drugs.com discount card for users of drugs.com. Prices are for cash paying customers only and are not valid with insurance plans.