Levaquin, Levaquin Leva-Pak (levofloxacin)

What is Levofloxacin?

Levofloxacin is a fluoroquinolone used to fight bacterial accumulation in human body. It is an effective medication for treating bacterial infections in kidneys, bladder, sinuses, prostrate and skin.

Levofloxacin is widely prescribed for treating bacterial contamination that causes bronchitis or pneumonia. It is also used for treating people suffering from anthrax or plague.

Levofloxacin is used for some other health-related issues which may or may not be listed in this guide.

Important information

Use of Levofloxacin is not advisable if you have any muscular disorder or a past of myasthenia gravis.

Levofloxacin is known to cause swelling or tearing of tendons, a fibrous tissue that connects muscles to bones, especially Achilles’ tendon of heel. You become more susceptible to this problem when you are above 60, you are on steroids or if you have had a lung transplant, any kidney or liver disorder.

Discontinue the use of Levofloxacin once you notice severe pain, bruising, swelling, stiffness, tenderness and movement issues in your joint areas. Rest the joint till the time you receive medical attention.

Before taking this medicine

Do not use Levofloxacin if you are hypersensitive to levofloxacin or any other medications of similar nature such as gemifloxacin, moxifloxacin, ciprofloxacin, norfloxacin, ofloxacin and others.

Use of Levofloxacin is not advisable if you have any muscular disorder or a past of myasthenia gravis.

For ensuring the safety of medication, inform your doctor if you have:

  • Personal or family history of Long QT syndrome
  • Heart rhythm disorder; tell your doctor if you are taking any drug for it
  • Tendon disorders, arthritis or other joint difficulties
  • Any liver or kidney issues
  • Bone difficulties, muscle or nerve disorder
  • Seizures or epilepsy
  • History of allergic reactions due to antibiotics
  • A past of head or brain injury
  • Diabetes, expecially if you are on insulin or other oral medications
  • Hypokalemia i.e. a condition of low potassium content in blood
  • If you use blood dinners such as warfarin, Coumadin
  • If you undergone INR” or prothrombin time tests.

Levofloxacin is known to cause swelling or tearing of tendons, a fibrous tissue that connects muscles to bones, especially Achilles’ tendon of heel. You become more susceptible to this problem when you are above 60, you are on steroids or if you have had a lung transplant, any kidney or liver disorder.

FDA pregnancy category C: It is unclear whether Levofloxacin causes damage to fetus. Inform your physician if you detect your pregnancy or have plans to conceive while using Levofloxacin. Excretion of this medication into human breast milk or possible adverse effect to nursing child is unknown. It is safe to avoid breastfeeding while using this medication.

Levofloxacin side effects

Call for medicinal help in case you feel ill or your condition worsens after intake of Levofloxacin. Flovent is known to cause some allergic reactions such as hives or skin rash, breathing difficulties and swelling in face, throat, lips and tongue.

Levofloxacin is known to cause swelling or tearing of tendons, a fibrous tissue that connects muscles to bones, especially Achilles’ tendon of heel. Stop taking this medication instantly and call your doctor if you notice:

  • Signs suggesting rupturing of tendons – bruising, tenderness, sudden pain, swelling, snapping or popping sound in any of your joints and movement problems. Rest the joint till the time you receive medical attention.
  • Nerve symptoms – Tingling, burning pain, more sensitivity towards light touch, temperature or sense of body positioning and numbness.

Serious side effects of Levofloxacin are:

Headache, chest pain or angina, severe dizziness;

  • Fainting, heart pounding, irregular heartbeat, nausea;
  • Upper Stomach pain, itching, tired feeling, appetite loss and dark urine;
  • Clay-colored stool and yellowing of skin and eyes (Jaundice)
  • Muscle weakness or trouble breathing;
  • Watery and bloody Diarrhea
  • Sudden weakness and tiredness, fever, sore throat, chills, mouth sores, easy bruising or bleeding;
  • Confusions, depression, hallucinations, tremors, paranoia;
  • Anxiety, insomnia, unusual thoughts or behavior, nightmares;
  • Seizures or convulsions;
  • Excessive pressure inside skull – ringing in your ears, severe headaches, dizziness, vision problems, pain behind your eyes;

Common ones are constipation, mild diarrhea, dizziness and headache.

Note: Apart from above mentioned, there are few other side effects of Levofloxacin. If case you feel extremely unwell, immediate medical attention is required. You may report the matter to FDA at 1-800-FDA-1088 FREE

What other drugs will affect Levofloxacin?

Levofloxacin can react with many medications. Inform your specialist about all medications you use before using this medication. Levofloxacin may interact with:

  • theophylline;
  • a diuretic or “water pill”;
  • heart rhythm medication– disopyramide, dofetilide, amiodarone, dronedarone, quinidine, sotalol, procainamide, and others;
  • NSAIDs (nonsteroidal anti-inflammatory drugs)– ibuprofen (Advil, Motrin), aspirin, celecoxib, diclofena, naproxen (Aleve), indomethacin, meloxicam, and others.
  • medicine to treat depression or mental illness– imipramine, nortriptyline, clomipramine, desipramine, amitriptylline, iloperidone and others; or

Note: This is not a comprehensive list and other drugs can also react to Levofloxacin. Inform about all your medications to your specialist. This includes prescribed and over-the-counter drugs, health or dietary supplements and Ayurvedic or herbal products. While on Levofloxacin, don’t start a new medication without your doctor’s guidance.

What happens if I miss a dose?

In case you miss a dose, take it as soon as you recall it. If it is time for your next scheduled intake, do not take your skipped dose. Do not consume extra medication for replenishing missed dose.

What happens if I overdose?

Strive to urgent medical care or call local Poison Help Centre at 1-800-222-1222 FREE.

What should I avoid?

Do not consume any other medication at the same time when you consume Levofloxacin. Certain medications can make Levofloxacin less effective. Do not take below mentioned drugs for 2 hours before or after using Levofloxacin:

  • Didanosine (Videx) powder or chewable tablets; or
  • Vitamin or mineral supplements containing iron, zinc, aluminum, and magnesium.
  • Antacids containing magnesium or aluminum (Mylanta, Rolaids or Maalox), or any ulcer medicine such as sucralfate (Carafate);

Levofloxacin makes you more sensitive towards sunlight and thus do not expose yourself to sunlight or tanning beds. This may result in sunburn. Use of full length clothes and good sunscreen cream (SPF 30 or higher) is advisable. Seek medical assistance in case you notice itching, rash, redness, burning, blistering and swelling of skin.

Levofloxacin may cause thinking impairment. Be careful while driving or undertaking similar activity as you may feel dizzy. Be alert.

Antibiotics can cause diarrhea that can be regarded as new signal of new infection. In case you suffer from watery and bloody diarrhea, discontinue Levofloxacin and inform your medical adviser. Use diarrhea medication keeping your doctor in loop.

How should I take Levofloxacin?

Follow doctor’s guidance and directions on prescription manual while using Levofloxacin. Do not increase or decrease the dosage amount on your own. Take it as recommended.

Levofloxacin must be used same time daily with a glass of water (8 ounces). You can take this medication with or without food. You are advised to consume enough fluids while using Levofloxacin.

In case you are using Levofloxacin oral suspension (liquid), take it 1 hour before or two hours after your meal empty stomach. Use a dose-measuring device for ensuring the right amount of dosage for you. If you do not have this device, ask your pharmacist.

Take Levofloxacin for the prescribed duration of time and complete the course even if you feel better. Do not abandon the course in the mid as it may reduce the effectiveness of medicine by development of resistance by bacteria towards it.

Levofloxacin is not for viral infections such as fever and common cold.

This medication may result in you having a false positive drug screening test. Before handling your urine sample for tests, tell the laboratory assistant about your consumption of Levofloxacin.

Do not share this medication with anyone having same symptoms. Consult a doctor first.

Store Levofloxacin at Room Temperature. Do not expose the medication in heat and moisture. Close bottle’s cap tightly when not in use.

Reviews for Levofloxacin

For Sinusitis: Levofloxacin gave me immense relief from my sinus pain.

I have had sinus infections my whole life and I am allergic to amoxicillin & erythromycin so I’ve taken Zithromax 100s of times. My sinusitis just started affecting my ear so a few months ago I tried 500mg x 5 days of Levofloxacin. I felt immediate relief although, at age 26, I couldn’t walk without my knees giving out! I never wanted to take it again. Fast forward to 5 days ago when I was in the Urgent Care for a horrible sinus & ear infection. Z-Pack hadn’t worked. I was in so much pain I decided to try Levofloxacin again. Day 5 of 10 500mg my body has tolerated it A LOT better! I feel great! Very little joint pain and almost immediate sinus and ear pain relief!

Levofloxacin for Urinary Tract Infection: I swear by Levofloxacin! It’s what works for me. I spent so much money on Amoxicillen, Z-Pack etc… and it doesn’t help. I have used it from a sinus infection, UTI, and pulmonary illnesses. It’s the medicine of choice for me. I have never experienced any side effects or adverse reactions. I’m very compliant with taking it daily, there have been times I missed doses because they’re prescribed 3-4x a day. It’s fast acting and does the trick, love it. I do think about becoming resistant to Levofloxacin, down the road, but by that time hopefully there will be another medicine of choice that is equally as effective! Thanks.

Levofloxacin for Sinusitis: I started Levofloxacin four days ago….noticed that I couldn’t sleep the first night. I have a sinus infection with a bad cough. The cough has improved, but still have drainage and eye pain. I asked the doctor for sleep medication which he gave me so I have no problem with that now. Eating lots of yogurt and taking probiotics and drinking lots of fluids. Still, the infection may not respond to this antibiotic as I have had the infection on and off for several months. Used this antibiotic as a last resort. Hopefully, it will clear up soon.

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