Ulcerative Colitis is a type of inflammatory bowel disease, also referred to as IBD, that affects the large intestine or colon. It is characterized by rectal bleeding, diarrhea, and abdominal cramps. The cause of the disease is not known but it has been found that eating certain foods can aggravate the symptoms of the disease. The disease can also cause joint, spine, skin, eyes and bile ducts inflammation. Treating ulcerative colitis usually involves the use of medication and surgery. This is where Mesalamine comes in. Mesalamine is a drug that was manufactured to help those exhibiting and suffering from both mild and moderately active symptoms of ulcerative colitis in patients. It helps to fight against the symptoms of ulcerative colitis by targeting the parts of the colon or large intestine that need the drug. You could say that the drug is like a missile that has its own automatic targeting system.
Uses of Mesalamine
As said earlier, Mesalamine, or its brand names, is used to treat the symptoms caused by ulcerative colitis. It may also be used to treat Crohn’s disease, which is another inflammatory bowel disease (IBD), as well as other diseases that may not be listed in this article. This means that your healthcare professional might prescribe the medication for you to treat the symptoms of another disease. Mesalamine is known as an amino salicylate that works by reducing swellings in the large intestine or colon.
Properties of Mesalamine
Mesalamine delayed-release (DR) tablets contain 400 mg each of Mesalamine, which is an anti-inflammatory drug itself. With a molecular weight of 153.1 and a molecular formula of C7H7NO3, Mesalamine delayed-release tablets contain inactive ingredients such as lactose monohydrate, meth acrylic acid copolymer B, sodium starch glycolate, talc, red iron oxide, magnesium stearate, edible black ink, povidone, dibutyl phthalate, colloidal silicon oxide, and yellow iron oxide. Mesalamine has a chemical name of 5-amino-2-hydroxybenzoic acid and is soluble at a pH of 7 or more.
Dosages of Mesalamine are always prescribed by a doctor or healthcare professional. Dosages may also be prescribed based on factors that may include the patient’s health history and interaction with aminosalicylates. Mesalamine tablets must not be chewed, crushed, broken in half but must be swallowed whole. It is also preferable that you take Mesalamine tablets with a glass full of water.
Side effects and Precautions
The side effects of Mesalamine use may include nausea, severe stomach pain and cramps, bloody diarrhea, joint pain, shortness of breath, hives, chest pain, dizziness, changes in urine color or urine problems, jaundice, rapid weight gain, fever, sore throat, gas, headache, among other side effects.It is highly important and necessary that if you experience these side effects of using Mesalamine occur, you should emergency help and inform your doctor immediately. It is also advised that you stay away from foods that trigger symptoms of ulcerative colitis.
There are medications that interact with Mesalamine. It is important to note that your doctor or healthcare professional be informed of any medication that you may have used or are still using. These drugs may include antiviral medicines like cidofovir, Oxaliplatin, Carmustine, Aldesleukin, streptococci, ifosfamide; antibiotics such as Rifampin, capreomycin, vancomycin; NSAIDS (non-steroidal anti-inflammatory drugs) like diclofenac, aspirin, celecoxib, meloxicam, naproxen, indomethacin. Over-the-counter, herbal products and prescription medicines may also interact with Mesalamine. This is not a complete list of drugs that interact with Mesalamine. It is therefore advised that you inform your doctor or healthcare professional about any old or new medication that you have used or are about to use.
Frequently Asked Questions (FAQ)
Can I skip on the dosage?
No, you should not skip it unless your healthcare provider tells you to.
Can I take two doses at once?
No, you must not take two doses at once because you missed one dose. You should take the missed dose at the right time.
What should I do if I feel uncomfortable or weak?
You should notify your healthcare provider if you feel any changes in your body systems.