Oral tablet

  • Microzide is a drug used in treating high blood pressure in order to prevent strokes, heart attacks and kidney problems. Microzide is also used in reducing edema (extra fluid in the body). it can also be used to reduce shortness of breath.
  • Microzide is a capsule and comes in three strengths: 12.5mg, 20mg, and 50mg. Microzide can only be prescribed by a doctor.
  • Microzide is a brand name and its generic name is hydrochlorothiazide

What is microzide?

Microzide (hydrochlorothiazide) is a prescription diuretic (water pill) that is taken orally, this drug microzide is a capsule that comes in four strengths which are microzide 12.5mg, microzide 20mg,microzide 50mg, and microzide 100mg. The medication can only be prescribed by a doctor.Generic name for microzide is hydrochlorothiazide as the name microzide is a brand name.Microzide can be used as the sole therapeutic agent, or in combination with other antihypertensive drugs. But unlike other potassium sparing combination diuretic products, MICROZIDE (hydrochlorothiazide capsule) may be used in patients taking ACE inhibitors as wells as in those whom the development of hyperkalemia cannot be risked.

Uses of microzide

Microzide is used in the treatment/management of hypertension. Microzide is designed to help eliminate the accumulation of excessive fluid and swelling that is usually caused by congestive heart failure, cirrhosis of the liver, chronic kidney failure, corticosteroid medications, and nephrotic syndrome. Most blood pressure lowering medications, including hydrochlorothiazide, are prescribed together with other hypertensive products, along with dietary restrictions, exercise, and, in some cases, weight loss. Hydrochlorothiazide may also be prescribed to treat calcium-containing kidney stones because of its ability to decrease the amount of calcium excreted by the kidneys in the urine, in order wise reducing the level of calcium necessary to form these stones.

How microzide works

Microzide belongs to the therapeutic class known as Thiazide diuretic. Thiazide diuretic work by blocking the re-absorption of Na+ and Cl- ions, thereby increasing the quantity of Na+ traversing the distal tubule and the volume of water excreted. Also, decreases the excretion of Ca2+ and uric acid, may increase the excretion of iodide, and may reduce GFR.

Microzide dosage

Microzide can be taken with or without food.A dosage of microzide 12.5 to 50 mg once daily for hypertension treatmentFor the treatment of edema, most adults will take microzide 25 to 100 mg once a day or in divided doses.Don’t stop taking your regular microzide dosage even if you feel well because your blood pressure may still be high even when you don’t feel sick.It’s not a good idea to take microzide within four hours of going to bed since it may result in your having to urinate during the night.

Microzide side effects

Common side effects of microzide are

  • Thirst
  • Muscle weakness
  • Constipation
  • Blurred vision
  • Dizziness
  • Photosensitivity

Serious side effects of microzide are

  • Severe allergic reaction (rash, hives, difficulty breathing, swelling of face, lips, tongue, or throat)
  • Severe stomach pain, loss of appetite, dark urine, or clay colored stools
  • Bleeding or bruising that seems unusual
  • A severe skin rash which includes peeling skin
  • Heartbeats that are fast or uneven
  • Tingling or numbness
  • Skin or eye yellowing (jaundice)

If you notice any of the following serious side effects, stop taking microzide and contact your doctor immediately.

Microzide interaction with other drugs

It’s very important to let your doctor know about all drugs you’re taking, including illegal drugs, any over-the-counter (OTC) drugs, and any herbs or supplements. Before taking microzide, let your doctor know if you’re using any of the following drugs:Lithium/Eskalith (Lithobid), Digoxin/Lanoxin, Cholestyramine/Prevalite, Cholestyramine (Questran), Colestipol/Colestid, Phenobarbital (Luminal) and Secobarbital (Seconal). Also taking digoxin with microzide may worsen cardiac arrhythmias because of the potassium-lowering effects of microzide.Cholestyramine and colestipol may decrease the absorption of microzide. If you’re taking either one, do so at least four hours before or after taking hydrochlorothiazide.